ENDONEXT™ Endotoxin Detection Assays
Based on Recombinant Horseshoe Crab Factor C (rFC), the ENDONEXT range of assays by bioMérieux is the future of endotoxin testing systems. With improved specificity, better consistency, and a more efficient workflow, ENDONEXT technology also completely eliminates the need to harvest horseshoe crabs for their blood—ushering in a new era of smarter, more sustainable pharmaceutical quality control.
All ENDONEXT assays follow BET methodology and are validated according to standard pharmacopoeial criteria. Since 2016, rFC is included in the European Pharmacopoeia chapter Ph. Eur. 5.1.10.
ENDOZYME® II GO
NEW 2018: The rapid GO version of ENDOZYME® II featuring GOPLATE™—a microplate pre-filled with required standard curve and positive product control concentrations (PPC).
• Eliminates manual preparation of standard dilutions and PPCs
• Over 50% reduction in handling time compared to conventional microplate assays
• Significantly reduces risk of error
• Ideal for in-process control of water and raw materials as well as product release testing
• Easy automation
ENDOZYME® II
ENDOZYME® II is the enhanced second generation of ENDOZYME®, a flexible and easy-to-use endotoxin detection assay offering state-of-the-art test performance.
• Test sensitivity down to 0.001 EU/mL
• Flexible assay time depending on required sensitivity
• Excellent lot-to-lot reproducibility
• Particularly suited for final product testing, formulation and research
ENDOLISA®
With its unique built-in sample preparation step, the ENDOLISA® assay revolutionizes endotoxin testing of complex samples.
• ELISA-like format features 96-well plate pre-coated with a specific endotoxin-binding phage protein
• Overcomes limits of traditional methods such as inhibition and enhancement
• Unprecedented tolerance of organic solvents, detergents, and chaotropic agents
• Low to no dilution of samples