Biofire Joint Infection panel


BENEFITS OF BIOFIRE® JOINT INFECTION

Simple Workflow

All-in one system, fully integrated and continuous-access testing.

2 minutes of hands-on time, at any time, by any tech, for any size of laboratory.

Only 0.2mL of synovial fluid.

Comprehensive Menu

39 clinically relevant targets in one test. The BIOFIRE® Joint Infection Panel tests for a comprehensive grouping of Gram-positive and Gram-negative bacteria, yeast, and antimicrobial resistance genes most often associated with joint infections. The panel includes difficult to grow anaerobes and fastidious organisms. Thanks to its PCR technology, the panel allows the detection of polymicrobial infections.

Fast Results

Using high multiplex technology in one syndromic test, the BIOFIRE® Joint Infection Panel offers a rapid sample-to-answer turnaround of about 1 hour, without sacrificing performance.

Xray of a knee joint that is infected.

More Informed Decision Making

"Pathogen identification is a central component of septic arthritis in native joints and prosthetic joint infections treatment guidelines."1-5

The BIOFIRE® Joint Infection Panel can potentially aid in appropriate surgical decision making and reduce the time to effective therapy through rapid pathogen identification.

Broad Panel Menu

In about an hour, the BIOFIRE® Joint Infection Panel simultaneously targets a broad grouping of 31 causative pathogens and 8 antimicrobial resistance markers commonly associated with joint infections.

GRAM-POSITIVE BACTERIA

  • Anaerococcus prevotii/vaginalis
  • Clostridium perfringens
  • Cutibacterium avidum/granulosum
  • Enterococcus faecalis
  • Enterococcus faecium
  • Finegoldia magna
  • Parvimonas micra
  • Peptoniphilus
  • Peptostreptococcus anaerobius
  • Staphylococcus aureus
  • Staphylococcus lugdunensis
  • Streptococcus spp.
  • Streptococcus agalactiae
  • Streptococcus pneumoniae
  • Streptococcus pyogenes

GRAM-NEGATIVE BACTERIA

  • Bacteroides fragilis
  • Citrobacter
  • Enterobacter cloacae complex
  • Escherichia coli
  • Haemophilus influenzae
  • Kingella kingae
  • Klebsiella aerogenes
  • Klebsiella pneumoniae group
  • Morganella morganii
  • Neisseria gonorrhoeae
  • Proteus spp.
  • Pseudomonas aeruginosa
  • Salmonella spp.
  • Serratia marcescens

ANTIMICROBIAL RESISTANCE GENES

mecA/C and MREJ (MRSA)
vanA/B

Carbapenemases

  • IMP
  • KPC
  • NDM
  • Oxa-48-like
  • VIM

ESBL

  • CTX-M

YEAST

  • Candida spp.
  • Candida albicans

The Syndromic Approach

Conventional testing for joint infections is complex, often requiring multiple patient samples, various send-out tests, and days of waiting for results. The BIOFIRE® Joint Infection Panel is a rapid syndromic test that delivers comprehensive results in one easy-to-read report. By targeting pathogens and antimicrobial resistance genes at the molecular level, syndromic infectious disease testing from BIOFIRE® is more sensitive than culture and more efficient than a serial approach involving individual and send-out tests.

Traditional method vs syndromic method process of testing synovial fluid.

Customer stories

Testimonials, Shared Experiences, and Clinical Cases

 

A testimonial about the BIOFIRE® Joint Infection Panel  

Dr. Susana Hartmann - Microbiologist
Vienna Orthopädisches Spital Speising GmbH (Austria)

A testimonial about the BIOFIRE® Joint Infection Panel

Dr. Jochen Hofstätter - Orthopedic Surgeon
Vienna Orthopädisches Spital Speising GmbH (Austria)

 

Potential impacts of the BIOFIRE® Joint Infection Panel

Dr. Jaime Esteban - Microbiologist
Fundacion Jimenez Diaz University Hospital, Madrid (Spain)

 

A multicenter evaluation and expert recomendations of use of the newly developed BIOFIRE® Joint Infection PCR Panel

Dr. Kordo Saaed - Consultant Microbiologist
Southampton University Hospitals (UK)


Information to download

BioFire® Joint Infection - Panel sheet

It contains the essential information on the panel, all on one sheet.

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Septic arthritis monograph

Septic arthritis, also known as infectious arthritis, is a severe type of orthopedic infection. Learn more in this monograph.

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BioFire® Joint Infection - White paper

Eight European experts on bone and joint infections giving their view of best positioning of the JI Panel.

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Other Available BIOFIRE® FilmArray® Panels

BIOFIRE®’s molecular solutions feature unmatched usability and speed, setting a new standard in molecular diagnostic platforms. The BIOFIRE® FilmArray® System and comprehensive panels empower all members of the care team to make better diagnostic decisions using the syndromic approach.

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