Biofire Meningitis and Encephalitis panel

World Meningitis Day

Every Minute Counts on World Meningitis Day.

 

At bioMérieux, we are dedicated to making a difference in the fight against encephalitis. On this World Meningitis Day, we want to emphasise the critical importance of early detection.

With our cutting-edge technology, including the BioFire® Meningitis/Encephalitis Panel, we enable early detection of this life-threatening condition in about one hour.

See below how the BioFire® can make an impact when the patient presents to A&E...

 

 UK & Ireland Meningitis Patient Pathway Video 

 

 

Clinical Case Study

 

KEY FACTS ABOUT MENINGITIS 1,2,3,4


• Meningitis is a severe infection of the central nervous system. It occurs when bacteria, viruses, or fungi infect the meninges, or tissue membranes that cover the brain and spinal cord. This causes inflammation of the membranes and accumulation of purulence
within the cerebrospinal fluid (see illustration below).
• Meningitis most commonly affects young children, the elderly, and immunocompromised people.
• Viral meningitis is the most common form and is usually a self-limited illness, although some viruses do respond to specific antiviral
treatment.
• Bacterial or fungal meningitis is a medical emergency which, if not treated rapidly, can lead to irreversible brain damage and death.

References:
1. WHO. Meningitis Fact Sheet. https://www.who.int/news-room/fact-sheets/detail/meningitis Accessed on September 29, 2023.
2. FCCMG Meningitis Blog. https://www.fccmg.com/blog/meningitis-symptoms-treatments/ Accessed on September 29, 2023.
3. NINDS. Meningitis and Encephalitis Fact Sheet. https://www.ninds.nih.gov/health-information/disorders/meningitis Accessed on September 29, 2023.
4. CDC. Meningococcal Disease. https://www.cdc.gov/meningococcal/about/risk-factors.html Accessed on September 29, 2023.

Webinar:
Navigating Meningitis: Insights from Patient and Clinician Perspectives

We were fortunate to work with the Meningitis Research Foundation to produce an educational webinar around navigating meningitis. The webinar gave an insight into a patient experience and difficulty of clinical diagnosis. 

Please click to assess and hear from Sharon and Dr Ali.  

Benefits of the ME Panel

FAST. EASY. COMPREHENSIVE.

Comprehensive Menu

The BIOFIRE® ME Panel tests for a comprehensive set of 14 of the most common bacterial, viral and yeast pathogens.

Rapid Results

  • Shorten time to diagnosis1,2,3

Impact antimicrobial therapy

  • Reduce both acyclovir and antibiotic duration4,5,6

Reduce length of stay

  • Reduction in length of stay for adult and paediatric patients2,4,1
REFERENCES
1.Mostyn, Amanda et al. “Assessment of the FilmArray® multiplex PCR system and associated meningitis/encephalitis panel in the diagnostic service of a tertiary hospital.” Infection prevention in practice vol. 2,2 100042. 11 Feb. 2020, doi:10.1016/j.infpip.2020.100042
2.Hueth, Kyle D et al. “Assessment of the Impact of a Meningitis/Encephalitis Panel on Hospital Length of Stay: A Systematic Review and Meta-Analysis.” Antibiotics (Basel, Switzerland) vol. 11,8 1028. 30 Jul. 2022, doi:10.3390/antibiotics11081028
3.Barry, R et al. “On-site Multiplex PCR for CSF diagnostics in an Acute Hospital versus Referral to Reference Laboratories: Assessing Economic Factors, Length of Stay and Antimicrobial Stewardship.” The Journal of infection vol. 82,3 (2021): 414-451. doi:10.1016/j.jinf.2020.10.004
4.Kadambari, Seilesh et al. “Evaluating the Impact of the BioFire FilmArray in Childhood Meningitis: An Observational Cohort Study.” The Pediatric infectious disease journal vol. 43,4 (2024): 345-349. doi:10.1097/INF.0000000000004236
5.Posnakoglou, Lamprini et al. “Impact of cerebrospinal fluid syndromic testing in the management of children with suspected central nervous system infection.” European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology vol. 39,12 (2020): 2379-2386. doi:10.1007/s10096-020-03986-6
6.Péan de Ponfilly, Gauthier et al. “Impact of a 24/7 multiplex-PCR on the management of patients with confirmed viral meningitis.” The Journal of infection vol. 83,6 (2021): 650-655. doi:10.1016/j.jinf.2021.08.050

 

BioFire® Meningitis/Encephalitis (ME) Panel Overview

1 TEST. 14 TARGETS. ~1 HOUR.

Panel Menu

Quickly distinguishing between bacterial meningitis and viral encephalitis is a matter of life and death – plus it can potentially avoid unnecessary admissions and help patients get on targeted treatment sooner. The BIOFIRE® ME Panel tests for a comprehensive set of 14 of the most common bacterial, viral and yeast pathogens and provide results in about 1 hour.

Provide Results in a Clinically Actionable Timeframe

workflow process of traditional vs syndromic testing

Information to download

BioFire® Meningitis/Encephalitis (ME) Panel Sheet

It contains the menu overview and shows the benefits of the ME Panel.

Download Now

BioFire® Meningitis/Encephalitis (ME) Pamphlet

It contains an overview of the Panel, the guidelines of the European Society of Clinical Microbiology and Infectious Diseases and shows the benefits of the ME Panel.

Download Now

 


Other Available BIOFIRE® FilmArray® Panels

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